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The Influence of Ayahuasca in problem-solving through a new responses chain

Authors

  • Sofia Azevêdo de Araujo Universidade Federal do Ceará
  • Daniely Ildegardes Brito Tatmatsu Universidade Federal do Ceará
  • Marcela Prata Oliveira Universidade Federal do Ceará
  • Leticia Santos Monteiro Universidade Federal do Ceará
  • Francisco Edimar Do Nascimento Junior Universidade Federal do Ceará

DOI:

https://doi.org/10.31505/rbtcc.v21i3.1329

Keywords:

Problem-solving behavior, Ayahuasca, Recombination of repertoires, Response Chaining, Behavioral Psychopharmacology

Abstract

Problem-solving behavior through a new responses chain happens when, facing a problem situation, a new response occurs resulted from the chaining of two or more independently learned answers. Objective: to evaluate the influence of ayahuasca in this process. Methodology: 12 male wistar rats were divided into groups: chronic, acute and control. The design was divided into: 1) habituation, 2) pre-test (open field/problem-solving), 3) training of the responses, 4) post-test (open field/ problem-solving). The substance was administered via gavage (2 ml/kg) to animals in the chronic group from phase 4 to 6, and in the acute group on stages 5 and 6. Animals in the control group ingested water. Results: There was no influence on problem-solving behavior, but there was in the training fase, which was slower for the chronic group. In the open field, there was a decrease in locomotor and exploratory activity in animals under the effect of ayahuasca.

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Published

2019-12-30

Versions

How to Cite

de Araujo, S. A., Tatmatsu, D. I. B., Oliveira, M. P., Monteiro, L. S., & Junior, F. E. D. N. (2019). The Influence of Ayahuasca in problem-solving through a new responses chain. Brazilian Journal of Behavioral and Cognitive Therapy, 21(3), 390–406. https://doi.org/10.31505/rbtcc.v21i3.1329

Issue

Vol. 21 No. 3 (2019): Especial: Criatividade

Section

Behavioral Pharmacology

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